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Extramammary Paget's disease
1Department of Internal Medicine and Pathology, Long Island College Hospital, Brooklyn, NY 11201, USA.
Southern Medical Journal
|August 3, 2000
Summary
Extramammary Paget's disease (EMPD) is a rare intra-epidermal neoplasm. Surgical resection with clear margins and follow-up are recommended due to high recurrence rates.
Area of Science:
- Dermatology
- Oncology
Background:
- Extramammary Paget's disease (EMPD) is an uncommon intra-epidermal neoplasm.
- It can be associated with invasive or in situ adenocarcinoma of apocrine glands, and potentially visceral carcinoma.
Observation:
- This review discusses two cases of EMPD.
- One case involved the perineal-scrotal area, and the other involved the perianal area.
Findings:
- Definitive diagnosis of EMPD requires biopsy and immunohistochemical staining.
- Noninvasive or minimally invasive EMPD typically requires surgical resection with clear margins.
Implications:
- Careful follow-up is crucial for EMPD patients due to a high recurrence rate.
- Understanding EMPD presentation and management is vital for dermatologists and oncologists.