Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hormone replacement therapy and the skin.

M P Brincat1

  • 1School of Human Development, Queens Medical Centre, University of Nottingham, Nottingham, UK.

Maturitas
|August 5, 2000
PubMed
Summary

Estrogen therapy improves skin quality and appearance by increasing collagen, thickness, and vascularization. It also benefits skin appendages like hair, reversing age-related skin deterioration.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of hormone replacement therapy on intervertebral disc height.

Climacteric : the journal of the International Menopause Society·2023
Same author

The urogenital system and the menopause.

Climacteric : the journal of the International Menopause Society·2015
Same author

Chemoprevention of breast cancer among women at elevated risk as defined by Gail Score.

Minerva ginecologica·2015
Same author

Estrogens and the intervertebral disc.

Menopause international·2009
Same author

Intervertebral disc height correlates with vertebral body T-scores in premenopausal and postmenopausal women.

Menopause international·2009
Same author

Urogenital atrophy.

Climacteric : the journal of the International Menopause Society·2009

Area of Science:

  • Dermatology
  • Endocrinology
  • Aging Research

Background:

  • Menopause-induced hypoestrogenism leads to significant skin deterioration.
  • Estrogen receptors are present in skin, with varying concentrations across body regions.
  • Estrogen influences skin structure and appendages, including collagen, thickness, vascularization, and hair follicle cycling.

Purpose of the Study:

  • To elucidate the multifaceted effects of estrogen on skin health.
  • To investigate estrogen's role in reversing menopause-related skin changes.
  • To explore the benefits of estrogen therapy for skin and its appendages.

Main Methods:

  • Identification of estrogen receptors within skin tissues.
  • Analysis of changes in skin collagen, thickness, and vascularization.
  • Assessment of extracellular matrix composition and hair follicle cycling.

Main Results:

  • Estrogen therapy demonstrably improves skin collagen content and quality.
  • Increased skin thickness and enhanced vascularization were observed with estrogen treatment.
  • Estrogen positively impacts skin appendages, notably increasing the hair follicle life cycle.
  • Estrogen replacement therapy reverses detrimental effects of estrogen deprivation on the skin.

Conclusions:

  • Estrogen plays a crucial role in maintaining skin health and reversing age-related changes.
  • Estrogen therapy offers significant benefits for skin structure, appearance, and appendages.
  • The skin is another organ system that benefits from hormone replacement therapy.

Related Experiment Videos