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Current concepts in androgen deprivation therapy--is there a "best" endocrine treatment?
1Department of Urology, University of Miami School of Medicine, Sylvester Comprehensive Cancer Institute, Florida, USA. egheiler@med.miami.edu.
World Journal of Urology
|August 5, 2000
Abstract:
Androgen deprivation therapy has become the mainstay treatment for locally advanced and metastatic prostate cancer. Castrate testosterone levels can be achieved by a multitude of treatments. We performed a medline literature search to answer the question, is there a "best" endocrine treatment? In conclusion we found that the "best" endocrine therapy for advanced prostate cancer is complete androgen blockade (CAB) with a luteinizing hormone-releasing hormone (LHRH) agonist and a nonsteroidal antiandrogen.