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Related Experiment Videos

Quality control in urinalysis.

T Takubo1, N Tatsumi

  • 1Department of Clinical and Laboratory Medicine Osaka City University Medical School, Osaka, Japan.

The Southeast Asian Journal of Tropical Medicine and Public Health
|August 5, 2000
PubMed
Summary
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Quality control (QC) surveys in urinalysis show satisfactory results for same-manufacturer reagents but highlight significant variations between different manufacturers and methods. Standardization of reagent strips, manual, and automated urinalysis methods, along with synthetic urine, is necessary.

Area of Science:

  • Clinical Chemistry
  • Laboratory Medicine
  • Urinalysis

Background:

  • Quality control (QC) is essential in laboratory diagnostics.
  • QC surveys in urinalysis are conducted by various professional organizations and manufacturers.
  • Previous surveys have assessed urinalysis performance using synthetic urine and automated analyzers.

Purpose of the Study:

  • To evaluate the performance of urinalysis methods using synthetic urine.
  • To identify variations in results obtained from different manufacturers and methods.
  • To assess the accuracy of urine sediment constituent identification in photo surveys.

Main Methods:

  • QC surveys were performed using synthetic urine with reagent strips and instruments from various manufacturers.
  • Automated urine cell analyzers were also utilized in the QC survey.

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  • A QC photo survey assessed the identification of urine sediment constituents.

    • Main Results:

    • Satisfactory results were observed for urinalysis using reagent strips and instruments from the same manufacturer.
    • Significant differences in determination values were found between different manufacturers and between manual and automated methods.
    • Variations in the identification of urine sediment cells were noted among laboratories in the photo survey.

    Conclusions:

    • The characteristics of reagent strips and instruments contribute to inter-manufacturer and inter-method variability.
    • Standardization of reagent strip methods is required.
    • Standardization of manual and automated urinalysis methods, as well as synthetic urine, is necessary for improved accuracy and consistency.