Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Familial Mediterranean fever.

N J Kubik¹, J D Katz

¹Hamot Medical Center, Erie, Pennsylvania, USA.

American Journal of Orthopedics (Belle Mead, N.J.)

|August 5, 2000

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Humoral and T-cell responses to SARS-CoV-2 vaccination in multiple sclerosis patients treated with ocrelizumab.

Multiple sclerosis and related disorders·2022

Same author

Pain does not suffer misprision: an inquiry into the presence and absence that is pain.

Medical humanities·2013

Same author

Issues of concern for the aging anesthesiologist.

Anesthesia and analgesia·2001

Same author

An aldol approach to the synthesis of the EF fragment of spongistatin 1.

Organic letters·2001

Same author

A case of Balamuthia mandrillaris meningoencephalitis.

Archives of neurology·2000

Same author

IL-10 deficiency does not inhibit insulitis and accelerates cyclophosphamide-induced diabetes in the nonobese diabetic mouse.

Cellular immunology·2000

Same journal

Unicondylar Knee Arthroplasty in the U.S. Patient Population: Prevalence and Epidemiology.

American journal of orthopedics (Belle Mead, N.J.)·2019

Same journal

Trends in Utilization of Total Hip Arthroplasty for Femoral Neck Fractures in the United States.

American journal of orthopedics (Belle Mead, N.J.)·2019

Same journal

The Characteristics of Surgeons Performing Total Shoulder Arthroplasty: Volume Consistency, Training, and Specialization.

American journal of orthopedics (Belle Mead, N.J.)·2019

Same journal

Review of Common Clinical Conditions of the Proximal Tibiofibular Joint.

American journal of orthopedics (Belle Mead, N.J.)·2019

Same journal

Return to Play After an Anterior Cruciate Ligament Injury: Prioritizing Neurological and Psychological Factors of the Decision-Making Algorithm.

American journal of orthopedics (Belle Mead, N.J.)·2019

Same journal

Preoperative Corticosteroid Use for Medical Conditions is Associated with Increased Postoperative Infectious Complications and Readmissions After Total Hip Arthroplasty: A Propensity-Matched Study.

American journal of orthopedics (Belle Mead, N.J.)·2019

See all related articles

Familial Mediterranean fever (FMF) is a genetic disorder causing painful attacks. Early consideration and colchicine treatment are key for managing FMF symptoms and preventing complications like amyloidosis.

Area of Science:

Rheumatology
Genetics
Internal Medicine

Background:

Familial Mediterranean fever (FMF) is an inherited multisystemic inflammatory disorder.
Diagnosis is challenging due to the lack of simple confirmatory tests.
FMF presents with recurrent febrile attacks affecting various body systems.

Observation:

A 10-year-old boy experienced recurrent joint and abdominal pain, initially treated with naproxen and omeprazole.
A 51-year-old man presented with fever, cough, and joint/abdominal pain.
Both patients eventually had Familial Mediterranean fever considered in their differential diagnosis.

Findings:

Colchicine is the gold standard treatment for FMF, effectively reducing attack frequency and severity.
Continuous colchicine therapy can prevent or delay secondary amyloidosis, a serious FMF complication.

Related Experiment Videos

Naproxen and omeprazole provided only intermittent relief in one FMF case.

Implications:

Highlights the diagnostic challenges in FMF, particularly in pediatric cases.
Emphasizes the critical role of colchicine in managing FMF and preventing long-term sequelae.
Suggests the need for increased awareness of FMF among clinicians to ensure timely diagnosis and treatment.