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Congenital ocular motor apraxia with autosomal dominant inheritance
P H Phillips1, M C Brodsky, P M Henry
1Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Purpose:
To document congenital ocular motor apraxia in five first-degree relatives.
Methods:
Case series. Five family members with a history of horizontal head thrusting had neuro-ophthalmologic evaluation. Magnetic resonance imaging of the brain was obtained in the proband.
Results:
Four siblings (one boy and three girls) had congenital ocular motor apraxia. The father had head thrusting as a child and displayed residual signs of the disorder. Magnetic resonance imaging disclosed no central nervous system abnormalities in the father.
Conclusion:
Congenital ocular motor apraxia can be inherited as an autosomal dominant trait.