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Blastocyst quality affects the success of blastocyst-stage embryo transfer
1Assisted Reproduction Unit, American Hospital of Istanbul, Istanbul, Turkey.
Objective:
To determine the relationship between blastocyst quality and the results of embryo transfer at the blastocyst stage.
Design:
Retrospective case analysis.
Setting:
Tertiary care private hospital IVF center.
Patient(S):
A total of 350 blastocyst-stage embryo transfer cycles.
Intervention(S):
In vitro culture to the blastocyst stage was undertaken in 350 ICSI cycles where four or more cleavage-stage embryos were available on day 3.
Main Outcome Measure(S):
Relationship between blastocyst quality and implantation and clinical and multiple pregnancy rates.
Result(S):
Transfer of at least one grade 1 or grade 2 blastocyst or one hatching blastocyst was associated with very high implantation and pregnancy rates. However, transfer of grade 3 blastocysts yielded very low implantation and pregnancy rates.
Conclusion(S):
There appears to be a strong correlation between blastocyst quality and success of blastocyst transfer.