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Updated: Aug 6, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
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1Age Concern Institute of Gerontology, Waterloo Wing, King's College London, Waterloo Rd, SE1 8WA, London, UK. robert.weale@kcl.ac.uk
Abstract:
Accommodative loss represents the fastest human biological decrement. Why? To examine this, the shape of the eye-lens during accommodation or its relaxation is analysed with special reference to age-related changes. The capsule is viewed as a force transmitter: the distribution of forces along centripetal capsular arcs and the resulting stresses and strains are calculated. The effect of zonular 'shifts' is considered. Age-related accommodative loss can be modelled successfully if changes in mechanical properties are linked to those in lenticular and capsular shape.
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