Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Pituitary stone--case report.

T Tamaki¹, I Takumi, T Kitamura

¹Department of Neurosurgery, Nippon Medical School, Tokyo.

Neurologia Medico-Chirurgica

|August 6, 2000

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Clinicopathological and immunohistochemical analysis of the risk factors of recurrence of atypical lipomatous tumor/well-differentiated liposarcoma of the extremities.

Acta orthopaedica Belgica·2025

Same author

Oral Health Interventions in Natural Disasters: A Scoping Review.

Disaster medicine and public health preparedness·2023

Same author

Investigation of factors related to the occurrence of osteochondral lesions of the talus by 3D bone morphology of the ankle.

The bone & joint journal·2018

Same author

A transfection method for short interfering RNA with the lipid-like self-assembling nanotube, A6K.

Medical molecular morphology·2013

Same author

Analysis of gene alterations of mitochondrial DNA D-loop regions to determine breast cancer clonality.

British journal of cancer·2012

Same author

Preoperative embolization of meningiomas with N-butyl cyanoacrylate.

Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences·2012

A rare pituitary stone within a growth hormone-secreting adenoma caused acromegaly. Surgical removal normalized hormone levels, offering insights into pituitary stone formation.

Area of Science:

Endocrinology
Neurosurgery
Pathology

Background:

Acromegaly is often caused by growth hormone-secreting pituitary adenomas.
Pituitary stones are rare, with calcifications typically found in the adenoma capsule.

Observation:

A 50-year-old male presented with acromegalic features and a growth hormone-secreting adenoma containing a large, intratumoral pituitary stone.
Endocrinological tests revealed paradoxical growth hormone responses, and neuroimaging confirmed the adenoma with calcification.

Findings:

Transsphenoidal surgery successfully removed the adenoma and pituitary stone.
Histological examination revealed the stone composed of calcification, necrotic adenoma tissue, and hemorrhage.
Post-surgery, the patient's growth hormone levels normalized, indicating successful treatment.

Related Experiment Videos

Implications:

This case highlights the rarity of large intratumoral pituitary stones.
The findings suggest that chronic disease progression and potential tumor apoplexy may contribute to pituitary stone formation.
Successful surgical intervention demonstrates a viable treatment option for such rare presentations.