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Does a herniated nucleus pulposus contribute significantly to a decrease in height of the intervertebral disc?

A I Holodny1, P S Kisza, S Contractor

  • 1Department of Radiology, UMDNJ-New Jersey Medical School, University Hospital C-320, Newark 07103-2714, USA. holodnai@umdnj.edu

Neuroradiology
|August 10, 2000
PubMed
Summary
This summary is machine-generated.

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Herniated nucleus pulposus (HNP) volume loss does not significantly decrease intervertebral disc height. The calculated height reduction is less than normal daily variations, suggesting HNP volume is not the primary cause of disc height reduction.

Area of Science:

  • Spine imaging and biomechanics
  • Radiology and diagnostic imaging

Background:

  • Lumbar intervertebral disc height reduction is often associated with herniated nucleus pulposus (HNP).
  • The extent to which HNP volume contributes to this height decrease is not fully understood.

Purpose of the Study:

  • To determine if the volume of herniated nucleus pulposus (HNP) is sufficient to cause a measurable decrease in lumbar intervertebral disc space height.
  • Quantify the relationship between HNP volume and intervertebral disc height.

Main Methods:

  • Magnetic Resonance Imaging (MRI) analysis of 44 patients with 51 HNPs.
  • Calculation of herniated material volume and parent intervertebral disc volume for levels L1-L2 to L5-S1.
  • Comparison of calculated disc height decrease with normal diurnal variations.

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Main Results:

  • Average HNP volume was 503 +/- 301 mm3, representing 3.5% of the parent disc volume.
  • Average intervertebral disc volume was 14,442 +/- 4200 mm3.
  • An average HNP resulted in a calculated intervertebral space height decrease of 0.35 mm (0.56 pixels).

Conclusions:

  • The volume of herniated nucleus pulposus (HNP) does not cause a significant decrease in intervertebral space height.
  • The average calculated decrease in disc height due to HNP is less than normal diurnal variations.