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Intraosseous microcystic meningioma
1Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Abstract:
Extradural ectopic meningioma is a rare tumor. We report on an example of microcystic meningioma arising in the skull of an elderly woman. Radiological examination revealed a localized osteolytic lesion in the left parietal bone. At surgery, it was discovered that the tumor was located within the skull without any evidence of extraosseous extension. The light microscopic, immunohistochemical and ultrastructural features were consistent with a microcystic variant of meningioma. To our knowledge, this is the first case of an intraosseous microcystic meningioma, and we believe that this type of meningioma should be considered in the differential diagnoses of myxoid bone tumors of the calvarium.
Insights
This study details a rare intraosseous microcystic meningioma in an elderly woman's skull. This finding expands the differential diagnosis for myxoid bone tumors of the calvarium.
Area of Science:
- Neurosurgery
- Oncology
- Pathology
Background:
- Extradural ectopic meningiomas are exceptionally rare tumors.
- Meningiomas typically arise from meningothelial cells outside the central nervous system.
Observation:
- A case of a microcystic meningioma presenting as an osteolytic lesion in the left parietal bone of an elderly woman is described.
- Radiological and surgical findings confirmed an intraosseous tumor without extraosseous extension.
Findings:
- Histopathological, immunohistochemical, and ultrastructural analyses confirmed the diagnosis of a microcystic meningioma variant.
- This represents the first reported instance of an intraosseous microcystic meningioma.
Implications:
- The findings suggest that intraosseous microcystic meningioma should be considered in the differential diagnosis of calvarial myxoid bone tumors.
- This case highlights the diverse presentations of meningiomas and the importance of comprehensive diagnostic evaluation.