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alpha-Amanitin: inactivation by bovine lactoperoxidase

P W Morris, K M Kelley, W G Logas

    Experientia
    |May 15, 1979
    PubMed
    Summary

    Alpha-amanitin, a key amatoxin, degrades rapidly with lactoperoxidase, iodide, and hydrogen peroxide. This process significantly reduces its ability to inhibit eukaryotic DNA-dependent RNA polymerase II.

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