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Related Experiment Videos

Botanical derivatives for the prostate.

A Cristoni1, F Di Pierro, E Bombardelli

  • 1Scientific Department, Indena S.p.A., Viale Ortles 12, 20139, Milan, Italy. indenami@tin.it

Fitoterapia
|August 10, 2000
PubMed
Summary
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Benign prostatic hyperplasia (BPH) and prostate cancer risk can be managed. Standardized plant extracts help control BPH symptoms, while lycopene shows promise in preventing and treating prostate cancer.

Area of Science:

  • Urology
  • Oncology
  • Pharmacognosy

Background:

  • Benign prostatic hyperplasia (BPH) is common after age 45, influenced by hormones like 5-alpha reductase.
  • Prostate tissue is also susceptible to neoplastic changes, leading to prostate cancer.
  • Epidemiological studies suggest a link between lycopene consumption and reduced prostate cancer incidence.

Purpose of the Study:

  • To explore the efficacy of plant extracts in managing BPH.
  • To investigate the role of lycopene in prostate cancer prevention and treatment.

Main Methods:

  • Utilizing highly standardized plant extracts (e.g., Pygeum africanum, Serenoa repens) for BPH.
  • Analyzing epidemiological data and clinical studies on lycopene's effects on prostate health.

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Main Results:

  • Plant extracts effectively control 5-alpha reductase activity and inflammation associated with BPH.
  • Lycopene demonstrates potential in both preventing prostate carcinoma and offering therapeutic benefits.

Conclusions:

  • Standardized botanical therapies offer a viable approach for BPH symptom management.
  • Lycopene presents a promising natural compound for prostate cancer chemoprevention and therapy.