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Grapefruit: the last decade acquisitions
1Istituto di Botanica, Università di Urbino Via Bramante, 28-61029, Urbino, Italy.
Fitoterapia
|August 10, 2000
Abstract:
This review reports the last decade acquisitions on grapefruit. New coumarins and limonoids were isolated and characterised. The bioavailability of many drugs was tested with grapefruit juice (GJ) coadministration; the inhibition on cytochrome P450 seems due to a synergic action between flavonoids and coumarins. Antimicrobial, antifeeding, insecticidal, and antitumour activities were also reported.