Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The evolution of base composition and phylogenetic inference.

Mooers, Holmes

    Trends in Ecology & Evolution
    |August 10, 2000
    PubMed
    Summary

    Genome base composition varies across species and evolutionary pressures, complicating phylogenetic tree reconstruction. Tree-based analyses are illuminating the general evolutionary forces driving these compositional changes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Reply to Yu and Chen.

    Liver international : official journal of the International Association for the Study of the Liver·2024
    Same author

    Abstracts and Selections.

    Texas medical journal (Austin, Tex.)·2023
    Same author

    ENHANCED RECOVERY PROTOCOL FOLLOWING AUTOLOGOUS FREE TISSUE BREAST RECONSTRUCTION.

    Acta chirurgiae plasticae·2020
    Same author

    Editor's Commentary.

    Current interventional cardiology reports·2000
    Same author

    Clinical Trials Review.

    Current interventional cardiology reports·2000
    Same author

    Interventional Cardiology: Where Do We Stand?

    Current interventional cardiology reports·2000

    Area of Science:

    • Genomics
    • Evolutionary Biology
    • Bioinformatics

    Background:

    • Genome base composition exhibits significant variation across all phylogenetic levels and genomic regions.
    • This variation is influenced by both active selection and passive mutation pressure.
    • Such compositional heterogeneity poses challenges for accurate phylogenetic tree reconstruction.

    Purpose of the Study:

    • To investigate the evolutionary forces shaping genome base composition.
    • To understand how base composition variation impacts phylogenetic analyses.
    • To highlight the utility of tree-based methods in evolutionary genomics.

    Main Methods:

    • Analysis of genome-wide base composition data.
    • Application of phylogenetic tree-based methodologies.
    • Comparative genomics across diverse taxa.

    Main Results:

    • Base composition variation is a pervasive feature across the evolutionary hierarchy.
    • Both selection and mutation pressure contribute to observed compositional patterns.
    • Tree-based analyses provide insights into the generality of evolutionary forces acting on base composition.

    Conclusions:

    • Understanding base composition dynamics is crucial for resolving phylogenetic relationships.
    • Phylogenetic tree-based approaches offer powerful tools for studying genome evolution.
    • Further research employing explicit tree-based methods is encouraged to explore these evolutionary forces.

    Related Experiment Videos