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AIDS myelopathy is not associated with elevated HIV viral load in cerebrospinal fluid
1Albert Einstein College of Medicine and Beth Israel Medical Center, New York, NY 10003, USA.
Neurology
|August 10, 2000
Abstract:
The pathogenesis of AIDS-associated myelopathy is unknown. Elevated HIV-1 viral load in CSF has been associated with cognitive impairment. The authors investigated if a similar association exists in patients with myelopathy. The authors evaluated levels of HIV-1 RNA in the CSF of 16 individuals with AIDS myelopathy and in 16 nonmyelopathic HIV-infected control subjects. There was no correlation between levels of HIV-1 RNA and the presence or severity of myelopathy.