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Related Experiment Videos

Adiposity and mortality in men.

I Baik1, A Ascherio, E B Rimm

  • 1Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA.

American Journal of Epidemiology
|August 10, 2000
PubMed
Summary

Higher body mass index (BMI) is linked to increased mortality risk in men under 65, but not older men. Waist circumference predicted cardiovascular disease deaths in older men, suggesting age-related differences in adiposity and mortality.

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Area of Science:

  • Epidemiology
  • Public Health
  • Gerontology

Background:

  • The relationship between body fat and mortality risk is complex and debated.
  • Previous studies have yielded conflicting results regarding adiposity measures and mortality outcomes.

Purpose of the Study:

  • To prospectively examine the association between various adiposity measures and overall/cause-specific mortality in US men.
  • To investigate how age influences the relationship between body fat and mortality.

Main Methods:

  • Prospective cohort study of 39,756 US men aged 40-75.
  • 10-year follow-up period (1986-1996) with documentation of mortality causes.
  • Analysis adjusted for potential confounders, including exclusion of early deaths and recent weight loss.

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Main Results:

  • Among men <65 years, higher body mass index (BMI) showed a linear increase in overall and cardiovascular disease mortality risk after excluding early deaths and weight loss.
  • For men aged 65+, BMI was not significantly associated with overall, cardiovascular disease, or cancer mortality.
  • Waist circumference was a significant predictor of cardiovascular disease mortality in older men.

Conclusions:

  • The association between adiposity and mortality is influenced by reverse causation and varies significantly by age.
  • BMI is a relevant mortality predictor for younger/middle-aged men, while waist circumference may be more critical for older men's cardiovascular health.