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Decoys 'R' Us: a database of incorrect conformations to improve protein structure prediction
1Department of Structural Biology, Stanford University School of Medicine, California 94305, USA. ram@csb.stanford.edu
Protein Science : a Publication of the Protein Society
|August 10, 2000
Abstract:
The development of an energy or scoring function for protein structure prediction is greatly enhanced by testing the function on a set of computer-generated conformations (decoys) to determine whether it can readily distinguish native-like conformations from nonnative ones. We have created "Decoys 'R' Us," a database containing many such sets of conformations, to provide a resource that allows scoring functions to be improved.