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The chicken B-cell receptor complex and its role in avian B-cell development

C E Sayegh1, S L Demaries, K A Pike

  • 1Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.

Immunological Reviews
|August 10, 2000
PubMed
Summary

Avian B-cell development in the bursa of Fabricius relies on a truncated mu chain for embryonic development. Post-hatch, antigen encounter drives B-cell proliferation and V gene diversification for immune repertoire formation.

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