Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Basic problems of serological laboratory diagnosis.

¹Institute for Clinical Microbiology and Immunology, St. Gallen, Switzerland.

Molecular Biotechnology

|August 10, 2000

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Basic problems of serological laboratory diagnosis.

Methods in molecular medicine·2011

Same author

Assessment of an Interferon-gamma release assay for the diagnosis of latent tuberculosis infection in haemodialysis patient.

Swiss medical weekly·2010

Same author

Expert opinion: guidelines for the use of natalizumab in multiple sclerosis patients previously treated with immunomodulating therapies.

Journal of neuroimmunology·2007

Same author

The SGML standardization framework and the introduction of XML.

Journal of medical Internet research·2001

Same author

Conception of an XML-based ontology for a Web-based medical information service.

Studies in health technology and informatics·2001

Same author

Sensitization to human immunodeficiency virus in seronegative exposed partners.

The Journal of infectious diseases·2000

Serological diagnostic tests indirectly measure the immune system

Area of Science:

Laboratory Medicine
Immunology
Infectious Diseases

Background:

Serological diagnosis relies on indirect measurement of immune responses.
Individual immune system variability complicates accurate interpretation.

Purpose of the Study:

To highlight inherent challenges in serological laboratory diagnosis.
To emphasize the need for improved standardization and interpretation.

Main Methods:

Analysis of the indirect nature of serological testing.
Examination of individual immune system variability and its impact.

Main Results:

Serological tests measure immune response, not disease or pathogen directly.
Unique antibody properties and personal history influence test outcomes.

Related Experiment Videos

Conclusions:

Complexities in test selection, interpretation, and standardization arise from these issues.
Close laboratory-clinical collaboration is essential for accurate patient care decisions.