Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human identity testing with PCR-based systems.

C Hohoff1, B Brinkmann

  • 1Institut für Rechtsmedizin, Universität Münster, Germany.

Molecular Biotechnology
|August 10, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Esketamine multi-omic biomarker evaluation in major depressive disorder (EMBER-MDD): concept, objectives and methodologies of a non-clinical investigator-initiated study.

European archives of psychiatry and clinical neuroscience·2026
Same author

The association between cytokines and cognitive function in patients with major depressive disorder and controls.

Journal of affective disorders·2024
Same author

Development and inter-laboratory evaluation of the VISAGE Enhanced Tool for Appearance and Ancestry inference from DNA.

Forensic science international. Genetics·2022
Same author

[Patio repair for urethrocutaneous fistulae : Results of a multicentre retrospective study].

Der Urologe. Ausg. A·2017
Same author

NPY+-, but not PV+- GABAergic neurons mediated long-range inhibition from infra- to prelimbic cortex.

Translational psychiatry·2016
Same author

The Necessity of Developing New Criteria for Carcinogen Classification of Fibers by the Mak Commission.

Inhalation toxicology·2015
Same journal

Optimizing miRNA Loading into Platelet Exosomes via Electroporation: A Comparative Analysis of Buffer Systems and Voltage Parameters for Enhanced Targeted Drug Delivery.

Molecular biotechnology·2026
Same journal

Regulation of Goat Milk Protein Synthesis: Genetic Architecture, Signalling Pathways, and Omics Insights.

Molecular biotechnology·2026
Same journal

Cloning and Functional Characterization of AhyAP-T65Lig, an ATP-Dependent DNA Ligase from Trabzonvirus AP-T65.

Molecular biotechnology·2026
Same journal

Overexpression of the ATP-Citrate Lyase Gene Enhances Ganoderic Acid Biosynthesis in Ganoderma lingzhi.

Molecular biotechnology·2026
Same journal

CRISPR/Cas9 Mediated Genome Editing for Enhancing Abiotic Stress Tolerance in Rice: An Omics Guided Perspective.

Molecular biotechnology·2026
Same journal

Functionalization of Chitosan with Silver Oxide and Berberis aristata for Bioactive Composites with In Vivo Wound Healing Evaluation.

Molecular biotechnology·2026
See all related articles

Short tandem repeats (STRs) are key DNA markers for human identification. This review covers STR molecular structure, PCR amplification, and analysis methods for DNA typing and human individuality.

Area of Science:

  • Genetics
  • Forensic Science

Background:

  • The human genome contains numerous polymorphic repetitive DNA sequences.
  • Microsatellites, or short tandem repeats (STRs), constitute about one-third of these repeats.
  • STRs are crucial for establishing human individuality.

Purpose of the Study:

  • To review the application of STRs in human identity testing.
  • To outline prerequisites for successful DNA typing using STRs.
  • To provide an overview of current and emerging STR analysis methods.

Main Methods:

  • Polymerase chain reaction (PCR) amplification of STRs.
  • Analysis of STR molecular structure from autosomes and the Y chromosome.
  • Comprehensive review of existing and novel STR analysis techniques.

Related Experiment Videos

Main Results:

  • STRs are highly valuable for state-of-the-art human identity testing.
  • Understanding STR molecular structure and PCR amplification is essential for accurate DNA typing.
  • A range of methods exist for STR analysis, with ongoing advancements.

Conclusions:

  • STR analysis is a powerful tool in forensic science and human identification.
  • The review provides a foundational understanding of STR typing methodologies.
  • Current and future STR analysis techniques offer enhanced capabilities for genetic profiling.