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[Multiple sclerosis incidence in the Alcoi Health district. 12-year-long study (1986-1997)]
J Mallada-Frechín1, J Matías-Guiu Guía, R Martín
1Unidad de Neurología, Hospital de Elda, España. jmalladaf@meditex.es
Revista De Neurologia
|August 10, 2000
Summary
This study tracked multiple sclerosis incidence in Spain over 12 years. Incidence rates increased significantly in the Alcoi district since the late 1980s, contrasting with earlier prevalence data.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Previous epidemiological studies on multiple sclerosis (MS) in Spain primarily focused on prevalence.
- Existing incidence data lacked standardized methodologies and clear inclusion criteria.
Purpose of the Study:
- To conduct a prospective, long-term incidence study of multiple sclerosis.
- To establish reliable incidence data using consistent diagnostic criteria.
Main Methods:
- Prospective data collection for definite multiple sclerosis cases over 12 years (1986-1997).
- Defined incidence year based on fulfillment of clinical diagnostic criteria for multiple sclerosis.
Main Results:
- Prevalence of clinically defined multiple sclerosis in Alcoi Health District was 41.28 per 100,000 inhabitants by Dec 1997.
- Average incidence was 2.82 cases per 100,000 inhabitants per year during the study period.
- Only 15 cases were diagnosed before 1986, with 45 diagnosed between 1986 and 1997.
Conclusions:
- This is the longest multiple sclerosis incidence study conducted in Spain.
- The observed incidence figures contrast with previous prevalence and incidence data.
- Multiple sclerosis incidence in the Alcoi district appears to have increased since the latter half of the 1980s.