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Common contact sensitizers in Delhi
1Department of Dermatology and STD, Maulana Azad Medical College & Loknayak Hospital, New Delhi, India.
The Journal of Dermatology
|August 10, 2000
Summary
This study found Parthenium, potassium dichromate, and xanthium are common allergens causing contact dermatitis in Indian adults. The Indian Standard Series is effective for diagnosis, with additions for local relevance.
Area of Science:
- Dermatology
- Allergology
- Epidemiology
Background:
- Contact dermatitis is a common skin condition with various causes.
- Identifying specific allergens is crucial for effective patient management.
- Previous studies have explored contact dermatitis prevalence globally and regionally.
Purpose of the Study:
- To investigate the prevalence and patterns of contact dermatitis in Indian patients.
- To identify common contact sensitizers using the Indian Standard Series and indigenous antigens.
- To evaluate the suitability of the diagnostic antigen series for the local population.
Main Methods:
- Patch testing was performed on 75 patients with suspected contact dermatitis.
- Patients were tested with the Indian Standard Series and locally relevant antigens.
- Results were analyzed to determine allergen prevalence and patient demographics.
Main Results:
- 65.3% of patients reacted to at least one allergen.
- Parthenium (20%), potassium dichromate (16%), and xanthium (13.33%) were the most frequent sensitizers.
- Hands were the most commonly affected site (40.83%), with chronic dermatitis being the predominant pattern.
Conclusions:
- The Indian Standard Series, supplemented with local allergens like garlic and onion, is effective for diagnosing contact dermatitis in India.
- Parthenium emerges as a significant contact allergen in the studied population.
- Understanding occupational profiles and common allergens aids in targeted prevention and treatment strategies.