Electron microscopic study of Langerhans cell histiocytosis
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M Kobayashi1, O Yamamoto, Y Suenaga
1Department of Dermatology, University of Occupational and Environmental Health, Kitakyushu, Japan.
The Journal of Dermatology
|August 10, 2000
Abstract:
Among the several forms of Langerhans cell histocytosis (LCH), Letterer-Siwe disease is the most acute disseminated multisystemic variant. The course of Letterer-Siwe disease is usually rapid and fatal. We report here a cases of Letterer-Siwe disease which showed a good response to chemotherapy. We also describe the unusual ultrastructural findings in the histiocyte-like cells in this case.
