Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Initial experience with the freestyle stentless aortic bioprosthesis.

S P Wong1, M E Legget, P J Raudkivi

  • 1Department of Cardiology, Green Lane Hospital, Auckland.

The New Zealand Medical Journal
|August 10, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fluctuation of BCR-ABL1 qPCR<sup>IS</sup> level beyond 0.1%<sup>IS</sup> after stopping tyrosine kinase inhibitor in chronic myeloid leukaemia patients with deep molecular response for at least two years.

The Medical journal of Malaysia·2021
Same author

Pseudoaneurysm of the radial artery following coronary angiography.

Herz·2013
Same author

Biological properties of sodium alkyl methyl ester sulfonate/alkyltrimethylammonium bromide surfactant mixtures.

Colloids and surfaces. B, Biointerfaces·2011
Same author

Ghrelin does not orchestrate the metabolic changes seen in fasting but has significant effects on lipid mobilisation and substrate utilisation.

European journal of endocrinology·2011
Same author

Non-viral S/MAR vectors replicate episomally in vivo when provided with a selective advantage.

Gene therapy·2010
Same author

Bioassays for estrogenic activity: development and validation of estrogen receptor (ERalpha/ERbeta) and breast cancer proliferation bioassays to measure serum estrogenic activity in clinical studies.

Assay and drug development technologies·2009

The Freestyle aortic bioprosthesis shows promising initial results, with no early mortality and good long-term clinical outcomes. This valve appears to be an excellent option for patients needing aortic valve replacement.

Area of Science:

  • Cardiovascular Surgery
  • Biomaterials Science
  • Medical Devices

Background:

  • Aortic valve disease, including stenosis and regurgitation, affects a significant patient population.
  • Bioprosthetic valves are a common solution for aortic valve replacement.
  • The Freestyle bioprosthesis is a newer option requiring evaluation of its performance.

Purpose of the Study:

  • To evaluate the initial clinical and hemodynamic performance of the Freestyle aortic bioprosthesis.
  • To assess early and late outcomes in patients receiving the Freestyle valve.
  • To determine the suitability of the Freestyle valve for aortic valve replacement.

Main Methods:

  • Implantation of the Freestyle prosthesis in 40 patients between 1993 and 1998.
  • Patients had diagnoses of aortic stenosis, regurgitation, or combined lesions.

Related Experiment Videos

  • Follow-up included clinical assessment, echocardiography, and monitoring for mortality and morbidity.

    • Main Results:

    • Zero early mortality and low early morbidity, with re-operations for bleeding as the most common complication.
    • One late death (non-valve related) and low rates of endocarditis and thromboembolic events at follow-up.
    • Significant improvement in New York Heart Association class and sustained regression of left ventricular mass, with satisfactory hemodynamic parameters.

    Conclusions:

    • The Freestyle aortic bioprosthesis demonstrates good early and late clinical and hemodynamic performance.
    • The valve shows potential as an ideal bioprosthesis for selected patients undergoing aortic valve replacement.
    • Further long-term studies are warranted to confirm these initial findings.