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Immunodiagnosis of chronic Chagas' disease using the Tc 46 and Tc 58 antigens

V R Pereira1, M Nakazawa, V C Furtado

  • 1Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhães/FIOCRUZ, Recife, PE, Brasil.

Revista Da Sociedade Brasileira De Medicina Tropical
|August 11, 2000
PubMed

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Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...