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Pancreatoblastoma. Three original cases and review of the literature
1Department of Radiology, Keio University School of Medicine, Tokyo, Japan.
Purpose:
To describe the characteristics of pancreatoblastoma.
Material And Methods:
We studied 3 cases of pancretoblastoma and reviewed another 59 cases. Parameters analyzed were tumor site, hemorrhage, capsule formation, necrosis, vascularity, production of alpha-fetoprotein (AFP), cystic changes and calcification.
Results:
The diagnostic findings were as follows: pancreatic head origin (24/54, 44%), pancreatic body and tail origin (30/54, 56%), hemorrhage (16/17, 94%), capsule formation (24/26, 92%), necrosis (28/31, 90%), hypervascularity (10/14, 71%), production of AFP (19/28, 68%), cystic changes (11/16, 69%), and calcification (10/21, 48%). All neonatal cases demonstrated cystic changes. Three of them were patients with Beckwith-Wiedmann syndrome. The incidence of capsule formation and calcification was not related to the origin of the tumor.
Conclusion:
The most common features of pancreatoblastoma are hemorrhage, capsule formation and necrosis.

