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Molecularly imprinted fluorescent-shift receptors prepared with 2-(trifluoromethyl)acrylic acid
1Laboratory of Synthetic Biochemistry, Faculty of Information Sciences, Hiroshima City University, Japan.
Analytical Chemistry
|August 12, 2000
Abstract:
Methacrylic acid (MAA) and 2-(trifluoromethyl)acrylic acid (TFMAA) were used to prepare molecularly imprinted polymers exhibiting diastereoselectivity for cinchona alkaloids. Fluorescent spectra of the cinchona alkaloid exhibit a characteristic shift through binding to these polymer particles, originating most likely from the highly acidic residues in the imprinted polymers acting as a proton donator. Our results show that TFMAA based imprinted polymers can be used as polymer reagents for quantitating the cinchona alkaloid bound to the polymers without bound/free separation.