Intrathyroid thyroglossal duct cyst simulating a thyroid nodule
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Updated: Oct 13, 2026

Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach
Published on: September 15, 2023
T Hatada1, S Ichii, K Sagayama
1The Second Department of Surgery, Hyogo College of Medicine, Japan.
Abstract:
A case of intrathyroid thyroglossal duct cyst is reported. A 50-year-old woman presented with a right lateral neck mass that was clinically indistinguishable from a thyroid nodule. Ultrasound-guided fine-needle aspiration biopsy (US-FNAB) revealed normal-looking squamous cells. Right thyroid lobectomy was performed and microscopic examination revealed a cyst lined by squamous epithelium that was consistent with a thyroglossal duct cyst. The lesion was completely surrounded by normal thyroid tissue. Our experience suggests that intrathyroid thyroglossal duct cyst should be remembered in the differential diagnosis of a thyroid nodule. Detection of benign squamous cells by US-FNAB may be useful for ruling out the possibility of a cystic thyroid tumor.
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