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Updated: Oct 13, 2026

Doppler Ultrasonography for Live Imaging and Quantification of Ovarian Vascular Function in Mice
Published on: November 14, 2025
Physiopathology of the renin-angiotensin system in the ovary
I De Nuccio1, G Salvati, G Genovesi
1Department of Medical Physiopathology, University of Rome La Sapienza.
Abstract:
The present review confirms the existence of the so-called "ovarian-derived prorenin-angiotensin cascade". It also describes the physiopathology of the system and, consequently, its role in the genesis of phenomena concerning reproductive function such as ovulation, steroid synthesis and folliculogenesis. Moreover, the "ovarian-derived prorenin-angiotensin cascade" appears to play an important role in the aetiopathogenesis of diseases such as ovarian tumours, ovarian hyperstimulation syndrome and ectopic pregnancy.
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