Related Experiment Video

Updated: Aug 11, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

Allergic colitis presenting in the first day of life: report of three cases

D Kumar1, A Repucci, J Wyatt-Ashmead

  • 1Department of Pediatrics, MetroHealth Medical Center, Cleveland, Ohio, USA.

Journal of Pediatric Gastroenterology and Nutrition
|August 15, 2000
PubMed

Insights

Allergic colitis in newborns presents with hematochezia and requires excluding other causes. Diagnosis involves infant appearance and specific tests, with treatment focused on antigen removal.

Area of Science:

  • Pediatric Gastroenterology
  • Neonatal Immunology

Background:

  • Allergic colitis is a potential cause of hematochezia in newborns.
  • It should be considered in the differential diagnosis of neonates presenting with rectal bleeding.

Observation:

  • Affected infants typically appear healthy.
  • Diagnosis is supported by proctosigmoidoscopy and histopathology.
  • Exclusion of infectious and anatomic disorders is crucial.

Findings:

  • Infants with allergic colitis often respond to antigen withdrawal.
  • Hydrolyzed cow's milk protein or elemental formulas are effective.
  • For breastfed infants, maternal dietary antigen elimination is key.

Implications:

  • Early diagnosis and management of allergic colitis improve infant outcomes.
  • Dietary modifications are the cornerstone of treatment.
  • Understanding allergic colitis is vital for neonatal care.

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