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Updated: Aug 19, 2026
05:51
A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
Published on: June 15, 2011
Identification of novel polymorphisms in the AXIN1++ and CDX-2 genes
Journal of Human Genetics
|August 17, 2000
Abstract:
Axin and Cdx-2 play important roles in the tumorigenesis of human liver and colon. We have identified seven novel single-nucleotide polymorphisms (SNPs) in the AXIN1 gene and three in the CDX-2 gene. The identification of SNPs in these cancer-associated genes establishes a basis for future investigations to detect losses of heterozygosity in tumors; these SNPs may also provide genetic background information associated with cancer risk.
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Exon shuffling follows “splice frame rules.” Each exon has three reading...
Exon shuffling follows “splice frame rules.” Each exon has three reading...