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Liquorice and its health implications.

A Olukoga1, D Donaldson

  • 1East Surrey Hospital, Redhill. aolukoga@hotmail.com

The Journal of the Royal Society for the Promotion of Health
|August 17, 2000
PubMed
Summary

Consuming liquorice can lead to apparent mineralocorticoid excess (AME) syndrome, causing health issues like high blood pressure and fluid retention. Awareness of liquorice toxicity is crucial for healthcare providers due to its widespread availability.

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Area of Science:

  • Pharmacology
  • Endocrinology
  • Toxicology

Background:

  • Liquorice is widely used in medicinal and confectionery products.
  • Its active metabolites can cause significant health issues.
  • Potential for widespread liquorice-induced morbidity exists.

Purpose of the Study:

  • To provide an overview of liquorice's health implications.
  • To highlight the risks associated with liquorice consumption.
  • To inform healthcare practitioners about liquorice toxicity.

Main Methods:

  • Literature review of liquorice health effects.
  • Analysis of mechanisms causing apparent mineralocorticoid excess (AME).
  • Discussion of clinical consequences and toxicity reports.

Main Results:

  • Liquorice ingestion can cause acquired apparent mineralocorticoid excess (AME) syndrome.
  • Symptoms include sodium retention, potassium loss, and renin-angiotensin-aldosterone system suppression.
  • Clinical effects include hypertension and edema.

Conclusions:

  • Easy availability of liquorice and its metabolites poses a substantial health risk.
  • Healthcare practitioners must be aware of liquorice-induced toxicity.
  • Understanding liquorice's adverse effects is vital for patient safety.

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