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Updated: Oct 13, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
[Aspiration of large intracoronary thrombus after apparently successful angioplasty. Therapeutic implications]
C Hernández1, J Goicolea, A Fernández-Ortiz
1Unidad de Hemodinámica y Cardiología Intervencionista, Hospital Clínico San Carlos, Madrid.
Insights
A large, recent thrombus was successfully removed after angioplasty for acute myocardial infarction, restoring normal coronary flow. This case highlights the importance of thrombus aspiration in interventional cardiology.
Area of Science:
- Interventional Cardiology
- Cardiovascular Pathology
Background:
- Optimal angioplasty following acute myocardial infarction (AMI) aims to restore coronary blood flow.
- Intracoronary thrombus can impede flow even after successful angioplasty procedures.
Observation:
- Despite optimal angioplasty for AMI with intracoronary thrombus, normal coronary flow was not achieved.
- Aspiration via the guiding catheter yielded a significant amount of thrombus.
Findings:
- Histopathologic examination confirmed the aspirated material as a recent thrombus.
- Successful thrombus aspiration reestablished normal coronary flow, enabling stent implantation.
Implications:
- Thrombus aspiration can be a critical adjunctive therapy when initial angioplasty fails to restore flow.
- This case underscores the diagnostic value of histopathologic analysis of aspirated thrombus.
- Effective management of intracoronary thrombus is crucial for optimal outcomes in acute myocardial infarction.
Abstract:
We present a case in which, after performing an optimal angioplasty after an acute myocardial infarction with intracoronary thrombus, normal coronary flow was not achieved. After aspirating through the guiding catheter we obtained a large thrombus that the histopathologic study confirmed as a recent thrombus and, subsequently, normal flow was reestablished. The procedure was completed with a successful intracoronary stent implantation, with an uneventful clinical course. The therapeutic and diagnostic implications of this case are discussed.
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