Related Experiment Video
Updated: Oct 13, 2026
Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome (ARDS)
Published on: September 7, 2016
One-lung flooding for video-assisted thoracoscopic surgery in animal experiments on pigs--oxygenation and
S Klinzing1, T Lesser, H Schubert
1Klinik für Anästhesiologie und Intensivtherapie, Friedrich-Schiller-Universität Jena, Germany. sklinzing.an.bacm.ukj@anae1.med.uni-jena.de
Abstract:
Unilateral flooding of the lung after intubation with a double-lumen tube makes intraoperative sonography of the lung during video-assisted thoracoscopic surgery possible. After flooding with 15 ml/kg, the arterial partial oxygen pressure (with FiO2=1.0) is higher than that in total atelectasis by about 100 mmHg, while it is only slightly less than that during bilateral lung ventilation. Compared to total atelectasis, lung flooding reduces the pulmonary right-to-left shunt volume. The pulmonary function normalizes within 8 h after the operation.
