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Thiazolidinediones, dyslipidaemia and insulin resistance syndrome
S Sunayama1, Y Watanabe, H Daida
1Department of Cardiology, Juntendo University, Tokyo, Japan. snym@med.juntendo.ac.jp
Current Opinion in Lipidology
|August 17, 2000
Abstract:
Insulin resistance is known to unite several metabolic abnormalities. The associated dyslipidaemia appears to play a central role in this atherogenic syndrome. Thiazolidinediones, which are recently introduced insulin sensitizing agents, have been shown to be effective not only in reducing elevated glucose levels, but also in improving the other metabolic abnormalities that are associated with insulin resistance. The present review focuses on these potential effects of thiazolidinediones.