DNA photolyases and cryptochromes
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Updated: Oct 13, 2026

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
Published on: June 15, 2017
1Howard Hughes Medical Institute and University of Texas Southwestern, Medical Center, Dallas, TX 75390-9050, USA. johann.deisenhofer@email.swmed.edu
Abstract:
This brief review gives an overview of the gene family of photolyases and cryptochromes, followed by a description of the main features of the three-dimensional structures of photolyases known to date. It then discusses recent biophysical studies of photolyase function, and modelling studies on the interaction between the enzyme and its substrate.
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