Related Experiment Video
Updated: Aug 7, 2026

Cercarial Transformation and in vitro Cultivation of Schistosoma mansoni Schistosomules
Published on: August 16, 2011
Studies on heterologous resistance between schistosomiasis mansoni and fascioliasis
A H Hafez1, M A Soliman, O A Hassounah
1Department of Parasitology, Faculty of Medicine Al-Azhar University, Cairo, Egypt.
Abstract:
S. mansoni and F. gigantica GSTs were purified from adult worm homogenates by affinity chromatography. Assessment of both SmGST and FgGST as candidate vaccines was done by comparing vaccinated mice groups challenged with S. mansoni cercariae with control ones in terms of worm load, tissue egg number viability and maturity, and the survival rate of the animals. SmGST 5 ug vaccination generally appeared to confer best protection against homologous challenge followed by FgGST 5 ug while vaccination with both antigens using low doses (2 ug) appeared to have no specific role in decreasing worm load but had significant effects on egg production.
Related Concept Videos
Malaria
Antiprotozoal Agents

