[Repeated exposure in hypergravity: morphology of locus coeruleus, hypothalamic paraventricular nucleus and vagal...

As compared to analogous single rotation at 2 g and in contrast to 5-d single and repeated exposures to Coriolis accelerations, repeated 5-day hypergravity (2 g generated by centrifuge rotation) gave rise to structural alterations in rat's neurons of locus coeruleus, vasopressinergic neurons of the lateral magnocellular subnucleus paraventricular nucleus and nervi vagi dorsal nucleus suggesting involvement of these structures of brain in the mechanism of facilitation of adaptation to repeated long-term hypergravity. Results of the study point to the ability of mammals to remember changes in gravity. Findings of the study may help develop an algorithm of intermittent exposure to artificial gravity aboard space vehicle.