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Giant cell arteritis and polymyalgia rheumatica: role of viral infections
P Duhaut1, S Bosshard, C Dumontet
1Department of Internal Medicine, Edouard Herriot Hospital, Lyon, France. pierre.duhaut@infonie.fr
Clinical and Experimental Rheumatology
|August 19, 2000
Abstract:
We performed a multicenter case-control study on incident cases of giant cell arteritis and polymyalgia, and tested for viruses known to induce multinucleated giant cells in human pathology. IgM directed against Human parainfluenza type 1 virus were shown to be significantly associated with the onset of the disease in 40% of the cases, versus 20% of the controls.