Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Case reports. Disseminated cryptococcoses without cryptococcal antigen detection.

K Tintelnot, S Adler, F Bergmann

    Mycoses
    |August 19, 2000
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Rare pancreatic tumors].

    Der Pathologe·2021
    Same author

    Radiological evaluation of pancreatic cancer: What is the significance of arterial encasement >180° after neoadjuvant treatment?

    European journal of radiology·2021
    Same author

    Impaired autophagy increases susceptibility to endotoxin-induced chronic pancreatitis.

    Cell death & disease·2020
    Same author

    Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma.

    International journal of cancer·2019
    Same author

    Validation of at least 1 mm as cut-off for resection margins for pancreatic adenocarcinoma of the body and tail.

    The British journal of surgery·2018
    Same author

    [Structured Curricular Advanced Education in "Medical Assessment" : Combined Concept of DGNB, DGN, DGNC, and DGPPN].

    Der Nervenarzt·2018

    Disseminated cryptococcosis is typically detected via cryptococcal antigen. However, three patients were diagnosed with disseminated cryptococcosis without detectable antigen, challenging diagnostic norms.

    Area of Science:

    • Mycology
    • Infectious Diseases
    • Immunology

    Background:

    • Cryptococcoses are fungal infections, frequently diagnosed in AIDS patients.
    • High levels of glucuronoxylomannan (GXM) are typically detected serologically in these cases.
    • Disseminated cryptococcosis is usually associated with detectable cryptococcal antigen.

    Observation:

    • Between August and October 1998, three consecutive patients were diagnosed with disseminated cryptococcosis.
    • Cryptococcal antigen was not detectable in any of these three patients.
    • Only one of the three patients diagnosed with disseminated cryptococcosis was HIV infected.

    Findings:

    • This case series highlights unusual presentations of disseminated cryptococcosis.
    • The absence of detectable cryptococcal antigen in disseminated disease is rare.

    Related Experiment Videos

  • Non-HIV infected individuals can also develop disseminated cryptococcosis without detectable antigen.

    • Implications:

    • Diagnostic strategies for cryptococcosis may need re-evaluation, especially in non-AIDS patients.
    • Further research is needed to understand the pathogenesis and diagnostic markers for cryptococcosis presenting without antigen.
    • This underscores the importance of considering clinical presentation alongside laboratory diagnostics in infectious disease management.