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Synergistic effect of amantadine and imipramine in the forced swimming test
1Department of Pharmacology, Institute of Pharmacology, Polish Academy of Sciences, Kraków.
Polish Journal of Pharmacology
|August 19, 2000
Abstract:
The obtained results indicate that joint administration of amantadine (a non-competitive NMDA receptor antagonist) and imipramine induced antidepressant-like effect in the forced swimming test even at doses of both drugs which were ineffective when each of the drugs was used alone.