Related Experiment Videos
Adrenal masses in the newborn
1Department of Surgery, Children's Hospital of Pittsburgh, and the University of Pittsburgh School of Medicine, Pennsylvania 15213, USA.
Seminars in Pediatric Surgery
|August 19, 2000
Summary
Neonatal adrenal tumors are rising due to better prenatal imaging. This review aids in diagnosing and managing these masses, considering both malignant and benign conditions.
Area of Science:
- Pediatric Oncology
- Diagnostic Imaging
- Neonatal Medicine
Background:
- Increasing incidence of neonatal adrenal tumors detected via prenatal ultrasonography.
- Adrenal and juxtarenal masses can be benign or malignant, with neuroblastomas historically guiding management.
- Recognition of benign juxtarenal lesions necessitates revised diagnostic approaches.
Purpose of the Study:
- To review major categories of neonatal adrenal masses.
- To propose a rational diagnostic and therapeutic algorithm.
- To address evolving management strategies for neonatal adrenal lesions.
Main Methods:
- Literature review of adrenal and juxtarenal masses in neonates.
- Analysis of diagnostic criteria and management outcomes.
- Synthesis of current understanding of tumor behavior and benign lesions.
Main Results:
- Neonatal neuroblastomas often exhibit benign behavior, prompting reevaluation of treatment.
- Benign juxtarenal lesions are increasingly recognized, challenging traditional diagnostic pathways.
- A significant proportion of neonatal adrenal masses are premalignant or malignant.
Conclusions:
- A refined diagnostic and management algorithm is needed for neonatal adrenal masses.
- Distinguishing between benign and malignant lesions is crucial for appropriate therapy.
- Updated guidelines should incorporate new insights into neuroblastoma behavior and benign juxtarenal masses.