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Parasite proteomics
J Barrett1, J R Jefferies, P M Brophy
1Institute of Biological Sciences, University of Wales, Aberystwyth, UK SY23 3DA. jzb@aber.ac.uk
Parasitology Today (Personal Ed.)
|August 22, 2000
Abstract:
Proteomics offers a new set of tools for investigating parasites and parasite-associated disease. In this article, John Barrett, Jim Jefferies and Peter Brophy describe the key technologies involved, including two-dimensional gel electrophoresis, image analysis, biological mass spectroscopy and database searching. The potential applications of proteomics in drug and vaccine discovery are reviewed, as are possible future developments.