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[Pasteurella multocida lung abscess. Study of a case with demonstration of a cat as vector]
V Grangeon1, H Lelièvre, M Celard
1Service de Pneumologie, Hôpital Louis Pradel, Lyon.
Revue Des Maladies Respiratoires
|August 22, 2000
Abstract:
We report a case of a lung abscess due to Pasteurella multocida, isolated from bronchial secretions by fiberoptic bronchoscopy. Antibodies against Pasteurella multocida were elevated in the patient, and absent in controls (including the patient's wife). The identity of the strain isolated in the patient and that in his cat was proved by molecular method using pulsed field gel electrophoresis.
Insights
A lung abscess caused by Pasteurella multocida was identified in a patient using fiberoptic bronchoscopy. Molecular analysis confirmed the bacteria strain originated from the patient's cat.
Area of Science:
- Infectious Diseases
- Microbiology
- Pulmonary Medicine
Background:
- Lung abscesses are serious infections, often caused by aspiration of oropharyngeal bacteria.
- Pasteurella multocida is a bacterium commonly found in the respiratory and oral tracts of domestic animals, particularly cats.
Observation:
- A patient presented with symptoms suggestive of a lung abscess.
- Fiberoptic bronchoscopy allowed for the collection of bronchial secretions for analysis.
- Elevated antibody titers against Pasteurella multocida were detected in the patient.
Findings:
- Pasteurella multocida was successfully isolated from the patient's bronchial secretions.
- Pulsed field gel electrophoresis (PFGE) confirmed the genetic identity between the bacterial strain from the patient and a strain isolated from the patient's cat.
- Antibodies against Pasteurella multocida were absent in control subjects, including the patient's wife.
Implications:
- This case highlights Pasteurella multocida as a potential pathogen in human lung abscesses, especially in individuals with animal contact.
- The findings underscore the importance of considering zoonotic sources in the etiology of pulmonary infections.
- Molecular typing methods are crucial for confirming the source of infection and understanding transmission pathways.