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Cerebellar cortical abiotrophy in two Portuguese Podenco littermates
S E van Tongern1, I K van Vonderen, J J van Nes
1Department of Veterinary Pathology, University Utrecht, The Netherlands.
The Veterinary Quarterly
|August 22, 2000
Abstract:
Cerebellar cortical abiotrophy in two Portuguese Podenco littermates is reported and discussed. The disease is characterized by progressive cerebellar ataxia with an early onset of two to three weeks. Extensive loss, degeneration, and necrosis of Purkinje cells particularly involved the cerebellar hemispheres. An autosomal recessive pattern of inheritance is suspected.