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Updated: Oct 13, 2026

Facial Nerve Surgery in the Rat Model to Study Axonal Inhibition and Regeneration
Published on: May 5, 2020
The abnormal nucleus as a cause of congenital facial palsy
B Jemec1, A O Grobbelaar, D H Harrison
1Department of Plastic Surgery, Mount Vernon Hospital, Rickmansworth Road, Northwood, Middlesex HA6 2RN, UK. bjemec@krota.domon.co.uk
Background:
Congenital facial palsy (CFP) is clinically defined as facial palsy present at birth. It is associated with considerable disfigurement and causes functional and emotional problems for the affected child. The aetiology of the majority of cases however, remains elusive.
Aims:
To investigate the role of a neuroanatomical abnormality as a cause of unilateral CFP.
Methods:
Magnetic resonance imaging (MRI) scans were performed on 21 patients with unilateral CFP. Fifteen patients had unilateral CFP only; six suffered from syndromes which can include unilateral CFP.
Results:
Of the 15 patients with unilateral CFP only, four (27%) had an abnormal nucleus or an abnormal weighting of this area on the MRI scan, compared to one (17%) of the remaining six patients.
Conclusion:
Developmental abnormalities of the facial nucleus itself constitute an important, and previously ignored, cause of monosymptomatic unilateral CFP.
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