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Balloon coarctation angioplasty: follow-up of 103 patients
S E Saba1, M Nimri, Q Shamaileh
1Providence Hospital and Medical Centers, Southfield, MI 48075, USA.
Insights
Balloon coarctation angioplasty (BCA) effectively manages native coarctation of the aorta, showing significant gradient reduction. This study supports BCA as a primary treatment option for aortic coarctation.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Pediatric Cardiology
Background:
- Coarctation of the aorta is a congenital heart defect requiring intervention.
- Balloon coarctation angioplasty (BCA) is a less invasive alternative to surgery.
- The efficacy of BCA for native coarctation remains a subject of ongoing research and debate.
Purpose of the Study:
- To assess the effectiveness of balloon coarctation angioplasty (BCA) in treating patients with native coarctation of the aorta.
- To evaluate hemodynamic changes and procedural outcomes following BCA.
- To determine the long-term role of BCA in the management of aortic coarctation.
Main Methods:
- A prospective study involving 103 patients with native coarctation of the aorta undergoing BCA.
- Hemodynamic parameters were measured before and immediately after the procedure.
- Follow-up evaluations were conducted at a mean of 26 months for a subset of patients.
Main Results:
- Successful reduction in systolic gradient from 59 mmHg to 10 mmHg (p < 0.001).
- The procedure achieved success in 82% of patients, with partial improvement in 17%.
- Repeat interventions were necessary for 13% of patients, and 8 patients required subsequent surgical intervention.
Conclusions:
- Balloon coarctation angioplasty demonstrates significant efficacy in reducing pressure gradients associated with native coarctation of the aorta.
- BCA is a viable and effective first-line treatment option for native coarctation of the aorta.
- The findings support the use of BCA as a primary intervention, potentially reducing the need for surgical repair in select patients.
Objective:
To evaluate the role of balloon coarctation angioplasty (BCA) in the management of patients with native coarctation of the aorta.
Background:
BCA has emerged as an alternative to surgery for patients with native coarctation of the aorta. However, its role remains controversial.
Methods:
Over a 7-year period, 103 patients undergoing BCA were enrolled in the study. Hemodynamic evaluation was obtained at baseline and immediately following BCA; 75% of patients returned for follow-up evaluation at 26 +/- 20 months.
Results:
The systolic gradient across the coarcted segment decreased from 59 +/- 18 mmHg to 10 +/- 11 mmHg following BCA (p < 0.001). The procedure was successful in 82% of patients, and partial improvement was obtained in 17%. Repeat intervention was performed in 13% of the follow-up group. Surgical intervention was needed in 8 patients.
Conclusion:
Balloon angioplasty is an effective first-line intervention in patients with native coarctation of the aorta.
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