[Teratogens during pregnancy]

To sum up the knowledge of the influence of substances in the external environment on the development of the human embryo/fetus during exposure at various periods of intrauterine life.

Summary.

Department of Obstetrics and Gynecology, 1st Faculty of Medicine, Charles University, Prague.

Compilation of data from scientific literature.

An overview of the main groups of teratogenic substances among the physical, chemical, biological and metabolic teratogens. Their relationship to morphological malformations, anomalies and functional defects are described.

A summary of the principles/basics of care of a pregnant woman using medication before or during pregnancy and the possibility of evaluating the individual reproductive risk during preconception and prenatal exposure to teratogenic substances.