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Updated: Aug 24, 2026

A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
Published on: December 20, 2014
[Urinary candidiasis revealed by ureteral obstruction: report of 2 cases]
A Benchekroun1, M Alami, M Ghadouan
1Clinique urologique A, hôpital Avicenne, CHU, Rabat, Maroc.
Abstract:
There has been an increase in the frequency of candidiasis urinary infections, which mainly affect diabetic or immunodepressed patients. However, the obstruction of the upper urinary tract by fungal infection is a rare occurrence. The introduction of novel antifungal agents has improved the treatment of fungal infection. In this study, two cases have been reported of urinary candidiasis infections with obstruction of the upper urinary tract which were successfully treated with fluconazole in combination with ureteral catheterization.
Insights
Urinary tract infections caused by Candida are increasing, especially in diabetic and immunocompromised patients. This study highlights successful treatment of rare upper urinary tract obstructions using fluconazole and ureteral catheterization.
Area of Science:
- Urology
- Infectious Diseases
- Mycology
Background:
- Urinary tract infections (UTIs) due to Candida species are becoming more frequent.
- These infections primarily impact individuals with diabetes mellitus or compromised immune systems.
- Upper urinary tract obstruction by fungal infection is an uncommon complication.
Observation:
- Two cases of urinary candidiasis presenting with upper urinary tract obstruction were identified.
- Patients had underlying conditions predisposing them to fungal infections.
Findings:
- Both cases were successfully treated with a combination regimen.
- The treatment involved the antifungal medication fluconazole and ureteral catheterization.
- This approach effectively resolved the obstruction and cleared the fungal infection.
Implications:
- This case series suggests that a combination of fluconazole and ureteral catheterization is an effective treatment strategy for obstructive urinary candidiasis.
- Early diagnosis and intervention are crucial for managing this rare but serious complication.
- Further research may explore optimal treatment durations and patient selection for this combined therapy.
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